custom reagents service
Our total synthesis based technology platform allows us to prepare ubiquitin and ubiquitin like protein reagents with various modifications.
assay reagents, probes, chains and ubiquitinated peptides
ubiquitin and ubiquitin-like proteins e.g. Nedd8, SUMO, ISG15 etc
electrophiles (warheads), peptides (substrate context), tags, unnatural amino acids
price & timelines
prices are on a project basis and bulk preparation (starting at 2 mg)
- 6 - 8 weeks lead time for most projects
>15 custom probes, >10 assay reagents, >9 ubiquitinated peptides:
- DUB specific assay reagents probes, HTRF assays, custom electrophiles, assays reagents and probes with substrate context
co-developed an antibody for yeast K123 Ub-H2B.
want to know more?
Please contact us at firstname.lastname@example.org to discuss your project and/or receive a detailed quote.
- Peptide pull-down assays with monoubiquitinated H2B & PTEN based peptides: R. Kessler et al. "dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes". Nat. Commun. 2015, 6, article number 7049. Doi: 10.1038/ncomms8049