reagents

  • Biotin-Ahx-SUMO2-Dha

    UbiQ code: UbiQ-159

    Biotin-Ahx-SUMO2-Dha (Dha= dehydroalanine) is a new and first of its kind activity based probe for the SUMO ligation pathway. [

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • Ub-VME

    UbiQ code: UbiQ-005

    Ub-VME is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs),

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • custom assay reagents

    UbiQ code: UbiQ-C01 ref PO

    Ubiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) assay reagents with various modifications (unnatural amino acids, peptides, tags, etc.)

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Biotin-Ahx-Ub-Dha

    UbiQ code: UbiQ-102

    Biotin-Ahx-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases including a biotin tag.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • His6-Ahx-Ahx-Ub-Dha

    UbiQ code: UbiQ-103

    UbiQ-103 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-103 is labeled with an His6 tag; two aminohexanoic acid (Ahx) linkers are used to create extra space between the His6 and Ub protein for efficient access of His6 binding entities.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • Biotin-Ahx-Nedd8-Dha

    UbiQ code: UbiQ-106

    Biotin-Ahx-Nedd8-Dha is a new activity based probe for Nedd8 E1, E2 and (HECT/RBR) E3 ligases.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • custom probes

    UbiQ code: UbiQ-C02

    Custom ubiquitin(-like) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5, biotin).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • custom peptides

    UbiQ code: UbiQ-C03

    Our UbiQ-PEP™ service provides isopeptide linked Ub-polypeptide conjugates with a range of modifications to meet your research needs.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling

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