reagents

  • Biotin-Ahx-SUMO2-Dha

    UbiQ code: UbiQ-159

    Biotin-Ahx-SUMO2-Dha (Dha= dehydroalanine) is a new and first of its kind activity based probe for the SUMO ligation pathway. [

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • His6-Ahx-Ahx-SUMO2-VPS

    UbiQ code: UbiQ-237

    His6-Ahx-Ahx-SUMO2-VPS (UbiQ-237) is an activity-based probe for SUMO proteases.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Ub-VME

    UbiQ code: UbiQ-005

    Ub-VME is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs),

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Biotin-Ahx-SUMO2-VME

    UbiQ code: UbiQ-156

    Biotin-Ahx-SUMO2-VME is an activity-based probe for SUMO proteases.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingDUB activity profilingtarget inhibitor profiling
  • Ac-ISG15prox-VPS

    UbiQ code: UbiQ-262

    UbiQ-262 is an activity-based probe for and inhibitor of ISG15 proteases

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • HA-Ahx-Ahx-Ub-VPS

    UbiQ code: UbiQ-193

    HA-Ahx-Ahx-Ub-VPS (UbiQ-193) is an activity-based probe and inhibitor of DUBs.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Biotin-ANP-Ub-PA

    UbiQ code: UbiQ-077

    Biotin-ANP-Ub-PA (UbiQ-077) is a newly developed potent and specific inhibitor of deubiquitylating enzymes (DUBs). It is labeled on the N-terminus with biotin and contains the UV cleavable 3-amino-3-(2-nitrophenyl)propanoic acid (ANP) linker, allowing for UV mediated cleavage of the biotin tag.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingDUB activity profilingtarget inhibitor profiling
  • Cy5-Ub-Dha

    UbiQ code: UbiQ-104

    Cy5-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-104 is labeled with a Cy5 tag.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • His6-Ahx-Ahx-Ub-Dha

    UbiQ code: UbiQ-103

    UbiQ-103 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-103 is labeled with an His6 tag; two aminohexanoic acid (Ahx) linkers are used to create extra space between the His6 and Ub protein for efficient access of His6 binding entities.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • Biotin-Ahx-Ub-Dha

    UbiQ code: UbiQ-102

    Biotin-Ahx-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases including a biotin tag.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • 5-carboxyRh110-Ub-Dha

    UbiQ code: UbiQ-131

    5-carboxyRh110-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • Biotin-Ahx-Nedd8-Dha

    UbiQ code: UbiQ-106

    Biotin-Ahx-Nedd8-Dha is a new activity based probe for Nedd8 E1, E2 and (HECT/RBR) E3 ligases.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • 5-carboxyRh110-Nedd8-Dha

    UbiQ code: UbiQ-122

    5-carboxyRh110-Nedd8-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-122 is labeled with the green fluorescent 5-carboxyrhodamine110 dye (cRh110).

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • custom probes

    UbiQ code: UbiQ-C02

    Custom ubiquitin(-like) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5, biotin).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling

14 Item(s)

per page