reagents

  • Ub-VME

    UbiQ code: UbiQ-005

    Ub-VME is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs),

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • HA-Ahx-Ahx-Ub-VPS

    UbiQ code: UbiQ-193

    HA-Ahx-Ahx-Ub-VPS (UbiQ-193) is an activity-based probe and inhibitor of DUBs.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • His6-Ahx-Ahx-SUMO2-VPS

    UbiQ code: UbiQ-237

    His6-Ahx-Ahx-SUMO2-VPS (UbiQ-237) is an activity-based probe for SUMO proteases.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Ac-ISG15prox-VPS

    UbiQ code: UbiQ-262

    UbiQ-262 is an activity-based probe for and inhibitor of ISG15 proteases

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • 5-carboxyRh110-Ub-Dha

    UbiQ code: UbiQ-131

    5-carboxyRh110-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • Cy5-Ub-Dha

    UbiQ code: UbiQ-104

    Cy5-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-104 is labeled with a Cy5 tag.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • 5-carboxyRh110-Nedd8-Dha

    UbiQ code: UbiQ-122

    5-carboxyRh110-Nedd8-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-122 is labeled with the green fluorescent 5-carboxyrhodamine110 dye (cRh110).

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • custom probes

    UbiQ code: UbiQ-C02

    Custom ubiquitin(-like) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5, biotin).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling

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