reagents

  • Ub-PA

    UbiQ code: UbiQ-057

    Ubiquitin-propargylamide is a newly developed potent and specific inhibitor of deubiquitylating enzymes (DUBs).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • Ub-VME

    UbiQ code: UbiQ-005

    Ub-VME is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs),

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • DUB activity based probe explorer panel

    UbiQ code: UbiQ-L02

    UbiQ-L02 is a panel of the following 10 deubiquitylating enzyme (DUB) activity based probes (ABPs).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • custom assay reagents

    UbiQ code: UbiQ-C01 ref PO

    Ubiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) assay reagents with various modifications (unnatural amino acids, peptides, tags, etc.)

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • Biotin-Ahx-Ub-PA

    UbiQ code: UbiQ-076

    Biotin-Ahx-Ub-PA (UbiQ-076) is a newly developed potent and specific inhibitor of deubiquitylating enzymes (DUBs), which is labeled on the N-terminus with biotin.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • K27 diUb-VME

    UbiQ code: UbiQ-083

    UbiQ-083 (K27 linked diUbiquitin VME) is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs) based on K27 linked diUb.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • K33 diUb-VME

    UbiQ code: UbiQ-085

    UbiQ-085 (K33 linked diUbiquitin VME) is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs) based on K33 linked diUb.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • K6 diUb-VME

    UbiQ code: UbiQ-081

    UbiQ-081 (K6 linked di-Ubiquitin VME) is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs) based on K6 linked diUb.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • Biotin-Ahx-Ub(1-75)-Dha-Ub

    UbiQ code: UbiQ-121

    UbiQ-121 is an activity based probe designed specifically to target deubiquitylating enzymes (DUBs) that recognize linear Ub-chains. The Gly-Met dipeptide between the two Ub proteins of a linear diUb has been replaced by a dehydroalanine-Met (Dha-Met) dipeptide, which reacts with OTULIN in a covalent manner.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • K48 diUb-VME

    UbiQ code: UbiQ-086

    UbiQ-086 (K48 diUbiquitin VME) is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs) based on K48 linked diUb.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profiling
  • custom probes

    UbiQ code: UbiQ-C02

    Custom ubiquitin(-like) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5, biotin).

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling
  • custom peptides

    UbiQ code: UbiQ-C03

    Our UbiQ-PEP™ service provides isopeptide linked Ub-polypeptide conjugates with a range of modifications to meet your research needs.

    crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling

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