reagents

  • SUMO3-Dha

    UbiQ code: UbiQ-118

    SUMO3-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.

    crystallizationwestern blot
  • SUMO1-Dha

    UbiQ code: UbiQ-116

    SUMO1-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.

    crystallizationwestern blot
  • 5-carboxyRh110-SUMO2

    UbiQ code: UbiQ-134

    human SUMO2 sequence (C48S) which is functionalized on the N-terminus with a 5-carboxyrhodamine110 dye.

    crystallizationMSphenotypic protein profilingtarget inhibitor profiling
  • His10-SUMO3-Dha

    UbiQ code: UbiQ-124

    His10-SUMO3-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.

    crystallizationwestern blot
  • SUMO2-Dha

    UbiQ code: UbiQ-117

    SUMO2-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.

    crystallizationwestern blot
  • Ub photoLeu73

    UbiQ code: UbiQ-154

    UbiQ-154 is a new crosslinking reagent based on ubiquitin in which Leu73 is replaced by the photoreactive analog photoleucine (photoLeu).

    crystallizationpull downwestern blotMS
  • Biotin-Ahx-SUMO2-Dha

    UbiQ code: UbiQ-159

    Biotin-Ahx-SUMO2-Dha (Dha= dehydroalanine) is a new and first of its kind activity based probe for the SUMO ligation pathway. [

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • His6-3C-MAP1LC3a-Dha

    UbiQ code: UbiQ-158

    UbiQ-158 is an activity-based probe for E1 activating enzymes and E2 conjugating enzymes that are involved in autophagy (e.g. ATG7 and ATG3, respectively). The N-terminus is labeled with an His6 affinity tag and a 3C protease cleavage site (QG), Cys17 has been mutated to a Ser residue (S).

    crystallizationwestern blot
  • customized assay reagents

    UbiQ code: UbiQ-C01 ref PO

    Ubiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) assay reagents with various modifications (unnatural amino acids, peptides, tags, etc.)

    DUB activity profilingcompound library screening
  • Biotin-Ahx-Ub-Dha

    UbiQ code: UbiQ-102

    Biotin-Ahx-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases including a biotin tag.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • 5-carboxyRh110-Ub-Dha

    UbiQ code: UbiQ-131

    5-carboxyRh110-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • Cy5-Ub-Dha

    UbiQ code: UbiQ-104

    Cy5-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-104 is labeled with a Cy5 tag.

    phenotypic protein profilingcompound library screeningtarget inhibitor profiling
  • Ub-Dha

    UbiQ code: UbiQ-101

    UbiQ-101 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.

    crystallizationwestern blot
  • His6-Ahx-Ahx-Ub-Dha

    UbiQ code: UbiQ-103

    UbiQ-103 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-103 is labeled with an His6 tag; two aminohexanoic acid (Ahx) linkers are used to create extra space between the His6 and Ub protein for efficient access of His6 binding entities.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling
  • Biotin-Ahx-Nedd8-Dha

    UbiQ code: UbiQ-106

    Biotin-Ahx-Nedd8-Dha is a new activity based probe for Nedd8 E1, E2 and (HECT/RBR) E3 ligases.

    crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling

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