reagents
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SUMO2-Dha
UbiQ code: UbiQ-117SUMO2-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.
crystallizationwestern blot -
Ub photoLeu73
UbiQ code: UbiQ-154UbiQ-154 is a new crosslinking reagent based on ubiquitin in which Leu73 is replaced by the photoreactive analog photoleucine (photoLeu).
crystallizationpull downwestern blotMS -
Biotin-Ahx-SUMO2-Dha
UbiQ code: UbiQ-159Biotin-Ahx-SUMO2-Dha (Dha= dehydroalanine) is a new and first of its kind activity based probe for the SUMO ligation pathway. [
crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling -
His6-3C-MAP1LC3a-Dha
UbiQ code: UbiQ-158UbiQ-158 is an activity-based probe for E1 activating enzymes and E2 conjugating enzymes that are involved in autophagy (e.g. ATG7 and ATG3, respectively). The N-terminus is labeled with an His6 affinity tag and a 3C protease cleavage site (QG), Cys17 has been mutated to a Ser residue (S).
crystallizationwestern blot -
SUMO3-Dha
UbiQ code: UbiQ-118SUMO3-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.
crystallizationwestern blot -
Ub-VME
UbiQ code: UbiQ-005Ub-VME is a potent, irreversible and specific inhibitor of deubiquitylating enzymes (DUBs),
crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling -
SUMO1-Dha
UbiQ code: UbiQ-116SUMO1-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.
crystallizationwestern blot -
5-carboxyRh110-SUMO2
UbiQ code: UbiQ-134human SUMO2 sequence (C48S) which is functionalized on the N-terminus with a 5-carboxyrhodamine110 dye.
crystallizationMSphenotypic protein profilingtarget inhibitor profiling -
His10-SUMO3-Dha
UbiQ code: UbiQ-124His10-SUMO3-Dha is a new and first of its kind activity based probe for the SUMO ligation pathway.
crystallizationwestern blot -
custom assay reagents
UbiQ code: UbiQ-C01 ref POUbiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) assay reagents with various modifications (unnatural amino acids, peptides, tags, etc.)
crystallizationpull downpurificationwestern blotMSNMRphenotypic protein profilingDUB activity profilingcompound library screeningtarget inhibitor profiling -
Ub-Dha
UbiQ code: UbiQ-101UbiQ-101 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.
crystallizationwestern blot -
His6-Ahx-Ahx-Ub-Dha
UbiQ code: UbiQ-103UbiQ-103 is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-103 is labeled with an His6 tag; two aminohexanoic acid (Ahx) linkers are used to create extra space between the His6 and Ub protein for efficient access of His6 binding entities.
crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling -
Biotin-Ahx-Ub-Dha
UbiQ code: UbiQ-102Biotin-Ahx-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases including a biotin tag.
crystallizationpull downpurificationwestern blotphenotypic protein profilingtarget inhibitor profiling -
5-carboxyRh110-Ub-Dha
UbiQ code: UbiQ-1315-carboxyRh110-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases.
phenotypic protein profilingcompound library screeningtarget inhibitor profiling -
Cy5-Ub-Dha
UbiQ code: UbiQ-104Cy5-Ub-Dha is a new activity based probe for Ub E1, E2 and (HECT/RBR) E3 ligases. The N-terminus of UbiQ-104 is labeled with a Cy5 tag.
phenotypic protein profilingcompound library screeningtarget inhibitor profiling