Our total synthesis based technology platform allows us to prepare Ubiquitin(-like) (e.g. Ub, Nedd8, SUMO, etc.) probes with various C-terminal warheads (e.g. VME= vinylmethyl ester, PA = propagylamide, VS= vinyl sulfone, Dha= dehydroalanine) and N-terminal tags (e.g. TAMRA, Cy5 and biotin).
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