Biotin-Ahx-Ub pThr7

Biotin-Ahx-Ub pThr7


UbiQ-092 is a ubiquitin protein that is phosphorylated on Thr7. Phosphoproteomic studies have identified several phosphorylated sites in ubiquitin, among them pThr7. It is labeled on the N-terminus with biotin; an aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and Ub protein for efficient access of biotin binding entities. It has been made by total chemical synthesis and is therefore well-defined in terms of biotin and pThr site and incorporation efficiency (100%).

Product Attachments

View FileUbiQ-092 Productsheet B01102014-001

Bennetzen et al. Mol Cell Proteomics 2010, 9, 1314.

Bian et al. J Proteomics 2014, 96, 253.

Kettenbach et al. Sci Signal, 2011, 4, rs5.

Sharma et al. Cell Rep 2014, 8, 1583.

Zhou et al. J Proteome Res 2013, 12, 260.

El Oualid et al. Angew Chem Int Ed 2010, 49, 10149.

pull downpurificationphenotypic protein profilingcompound library screening

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name Biotin-Ahx-Ub pThr7
product code UbiQ-092
Applications pull down, purification, phenotypic protein profiling, compound library screening
target n/a
source human, synthetic
shipping lyophilized powder
purity ≥95% by RP-HPLC and SDS-PAGE analysis
molecular weight 8.98 kDa
storage Powder at −20°C; buffered solution at −80°C. Please avoid multiple freeze/thaw cycles.
sample preparation For detailed sample preparation see product sheet.
regulatory statement For laboratory research use only, not for use in humans.